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Chemical structure of USP8-IN-1

GC64537

USP8-IN-1

Also known as 4-(2-amino-4-methoxyphenyl)-N-(4-nitrophenyl)piperazine-1-carbothioamide

USP8-IN-1 is a USP8 inhibitor with an IC50 of 1·9 μM· USP8-IN-1 inhibits H1975 cell growth with a GI50 of 82·04 μM (CN111138358A; U10)

ChemicalCAS2477650-96-5MW387.46FormulaC18H21N5O3S
CAS number
2477650-96-5
Molecular weight
387.46
Formula
C18H21N5O3S
Solubility
DMSO ： 125 mg/mL (322·61 mM; Need ultrasonic)
InChIKey
LYQOAIJZQPUZEF-UHFFFAOYSA-N
Catalogue number
GC64537
Brand
GLPBIO
Computed properties PubChem CID 163408888 · XLogP 2.4 · TPSA 132 Ų · H-bond donors 2
XLogP
2.4
TPSA
132 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
27

SMILES COC1=CC(=C(C=C1)N2CCN(CC2)C(=S)NC3=CC=C(C=C3)[N+](=O)[O-])N

Computed descriptors from PubChem (CID 163408888), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.