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Chemical structure of VEGFR-2-IN-39

GC71462

VEGFR-2-IN-39

Also known as (2S,4R)-1-[(2S)-2-[[12-[3-amino-4-[4-[(2-fluoro-5-methylphenyl)carbamoylamino]phenyl]indazol-1-yl]-12-oxododecanoyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

VEGFR-2-IN-39 (PROTAC-5) is a PROTAC targeting VEGFR-2 (IC50: 208·6 nM)

ChemicalCAS2353417-86-2MW1000.23FormulaC55H66FN9O6S
CAS number
2353417-86-2
Molecular weight
1000.23
Formula
C55H66FN9O6S
Solubility
DMSO ： 200 mg/mL (199·95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
YZGNCBAFOZBYKS-SHPBXJAASA-N
Catalogue number
GC71462
Brand
GLPBIO
Computed properties PubChem CID 141744224 · XLogP 9.7 · TPSA 242 Ų · H-bond donors 6
XLogP
9.7
TPSA
242 Ų
H-bond donors
6
H-bond acceptors
11
Rotatable bonds
21
Heavy atoms
72

SMILES CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)N(N=C4N)C(=O)CCCCCCCCCCC(=O)N[C@H](C(=O)N5C[C@@H](C[C@H]5C(=O)NCC6=CC=C(C=C6)C7=C(N=CS7)C)O)C(C)(C)C

Computed descriptors from PubChem (CID 141744224), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.