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Chemical structure of IRAK4-IN-20

GC71135

IRAK4-IN-20

Also known as N-[2-(3-hydroxy-3-methylbutyl)-6-(2-hydroxypropan-2-yl)indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide

IRAK4-IN-20 (Compound BAY-1834845) is an orally active IRAK4 inhibitor with an IC50 of 3·55 nM

ChemicalCAS1931994-80-7MW450.45FormulaC22H25F3N4O3
CAS number
1931994-80-7
Molecular weight
450.45
Formula
C22H25F3N4O3
InChIKey
NWFPCWIBSBZRGV-UHFFFAOYSA-N
Catalogue number
GC71135
Brand
GLPBIO
Computed properties PubChem CID 121364971 · XLogP 3.1 · TPSA 100 Ų · H-bond donors 3
XLogP
3.1
TPSA
100 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
32

SMILES CC(C)(CCN1C=C2C=C(C(=CC2=N1)C(C)(C)O)NC(=O)C3=NC(=CC=C3)C(F)(F)F)O

Computed descriptors from PubChem (CID 121364971), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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