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Chemical structure of IRAK4-IN-4

GC38799

IRAK4-IN-4

Also known as 1-(7-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)-2-phenylethane-1,2-dione

IRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2·8 nM

ChemicalCAS1850276-58-2MW340.37FormulaC22H16N2O2
CAS number
1850276-58-2
Molecular weight
340.37
Formula
C22H16N2O2
Solubility
DMSO: 25 mg/mL (73·45 mM)
InChIKey
AHNNWZOVCRQAAH-UHFFFAOYSA-N
Catalogue number
GC38799
Brand
GLPBIO
Computed properties PubChem CID 145712357 · XLogP 5.1 · TPSA 51.4 Ų · H-bond donors 0
XLogP
5.1
TPSA
51.4 Ų
H-bond donors
0
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
26

SMILES CC1=CC2=NC(=C(N2C=C1)C(=O)C(=O)C3=CC=CC=C3)C4=CC=CC=C4

Computed descriptors from PubChem (CID 145712357), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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