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Chemical structure of Akt1&PKA-IN-1

GC71063

Akt1&PKA-IN-1

Also known as N-[(R)-azetidin-3-yl-(3,4-dichlorophenyl)methyl]isoquinoline-6-carboxamide

Akt1&PKA-IN-1 is a potent dual Akt/PKA inhibitor with IC50 values of 0·03 , 0·11 μM, and 9·8 μM for PKAa, Akt, and CDK2, respectively

ChemicalCAS1334107-58-2MW386.27FormulaC20H17Cl2N3O
CAS number
1334107-58-2
Molecular weight
386.27
Formula
C20H17Cl2N3O
InChIKey
TWAIYMKBHKNSRO-IBGZPJMESA-N
Catalogue number
GC71063
Brand
GLPBIO
Computed properties PubChem CID 53386721 · XLogP 3.8 · TPSA 54 Ų · H-bond donors 2
XLogP
3.8
TPSA
54 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
26

SMILES C1C(CN1)[C@H](C2=CC(=C(C=C2)Cl)Cl)NC(=O)C3=CC4=C(C=C3)C=NC=C4

Computed descriptors from PubChem (CID 53386721), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.