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Akt1(Phospho-Ser473) Rabbit mAb

13357

Akt1(Phospho-Ser473) Rabbit mAb

Akt1(Phospho-Ser473) Rabbit mAb (catalogue number 13357) is a recombinant rabbit rabbit-derived recombinant phospho rabbit antibody validated for Western blot, ICC/IF, Immunohistochemistry, reactive with Human, Mouse samples. It targets RAC-alpha serine/threonine-protein kinase (AKT1): AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪1,749.85; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Recombinant Phospho Rabbit AntibodyHostRecombinant Rabbit Rabbit
Host / source
Recombinant Rabbit Rabbit
Reactivity
Human, Mouse
Applications
Western blot ICC/IF Immunohistochemistry
UniProt ID
P31749
Gene
AKT1
Target organism
Homo sapiens
Catalogue number
13357
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: RAC-alpha serine/threonine-protein kinase (AKT1) · Homo sapiens

AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported.

Subcellular location: Cytoplasm; Nucleus; Cell membrane; Mitochondrion intermembrane space

Tissue specificity: Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e.

Sequence length: 480 aa · 55686 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.