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Chemical structure of NCATS-SM4487

GC70688

NCATS-SM4487

Also known as 2-[(7-amino-6-fluoro-1,3-benzoxazol-2-yl)amino]-4-(2-chloro-4-methylphenyl)-6-methyl-N-[(1-methylpyrazol-4-yl)methyl]-1,4-dihydropyrimidine-5-carboxamide

NCATS-SM4487 is a highly selective unique dihydropyrimidine inhibitor against GALK1, with an IC50 value of 0·05 μM

ChemicalCAS2733617-81-5MW522.96FormulaC25H24ClFN8O2
CAS number
2733617-81-5
Molecular weight
522.96
Formula
C25H24ClFN8O2
InChIKey
QPSGQKPZSLFNCS-UHFFFAOYSA-N
Catalogue number
GC70688
Brand
GLPBIO
Computed properties PubChem CID 156898842 · XLogP 2.5 · TPSA 135 Ų · H-bond donors 4
XLogP
2.5
TPSA
135 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
37

SMILES CC1=CC(=C(C=C1)C2C(=C(NC(=N2)NC3=NC4=C(O3)C(=C(C=C4)F)N)C)C(=O)NCC5=CN(N=C5)C)Cl

Computed descriptors from PubChem (CID 156898842), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.