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Chemical structure of NCB-0846

GC19260

NCB-0846

Also known as 4-[2-(3H-benzimidazol-5-ylamino)quinazolin-8-yl]oxycyclohexan-1-ol

NCB-0846 is an orally available TNIK inhibitor with an IC50 of 21 nM

ChemicalCAS1792999-26-8MW375.42FormulaC21H21N5O2
CAS number
1792999-26-8
Molecular weight
375.42
Formula
C21H21N5O2
Solubility
DMSO : ≥ 30 mg/mL (79·91 mM)
InChIKey
FYWRWBSYRGSWIQ-UHFFFAOYSA-N
Catalogue number
GC19260
Brand
GLPBIO
Computed properties PubChem CID 91801204 · XLogP 3.6 · TPSA 96 Ų · H-bond donors 3
XLogP
3.6
TPSA
96 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
28

SMILES C1CC(CCC1O)OC2=CC=CC3=CN=C(N=C32)NC4=CC5=C(C=C4)N=CN5

Computed descriptors from PubChem (CID 91801204), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.