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Chemical structure of BI-1408

GC70338

BI-1408

Also known as N-[(5R)-1-ethyl-4,5,6,7-tetrahydroindazol-5-yl]-8-(4-fluoro-2-methylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

BI-1408 is a potent γ secretase modulator with an IC50 of 0·04 μM for Aβ42

ChemicalCAS2231075-94-6MW390.46FormulaC22H23FN6
CAS number
2231075-94-6
Molecular weight
390.46
Formula
C22H23FN6
InChIKey
OHXQPMCUJTWQJA-QGZVFWFLSA-N
Catalogue number
GC70338
Brand
GLPBIO
Computed properties PubChem CID 138319684 · XLogP 4.2 · TPSA 60 Ų · H-bond donors 1
XLogP
4.2
TPSA
60 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
29

SMILES CCN1C2=C(C[C@@H](CC2)NC3=NN4C=CC=C(C4=N3)C5=C(C=C(C=C5)F)C)C=N1

Computed descriptors from PubChem (CID 138319684), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.