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Chemical structure of BI-1347

GC35512

BI-1347

Also known as 2-[4-(4-isoquinolin-4-ylphenyl)pyrazol-1-yl]-N,N-dimethylacetamide

BI-1347 is an orally active, selective and potent CDK8 inhibitor (IC50=1·1 nM)· BI-1347 shows anti-tumoral activity

ChemicalCAS2163056-91-3MW356.42FormulaC22H20N4O
CAS number
2163056-91-3
Molecular weight
356.42
Formula
C22H20N4O
Solubility
DMSO： 125 mg/mL (350·71 mM)
InChIKey
WULUGQONDYDNKY-UHFFFAOYSA-N
Catalogue number
GC35512
Brand
GLPBIO
Computed properties PubChem CID 132180482 · XLogP 3.3 · TPSA 51 Ų · H-bond donors 0
XLogP
3.3
TPSA
51 Ų
H-bond donors
0
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
27

SMILES CN(C)C(=O)CN1C=C(C=N1)C2=CC=C(C=C2)C3=CN=CC4=CC=CC=C43

Computed descriptors from PubChem (CID 132180482), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.