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Chemical structure of PI3K/AKT-IN-1

GC69706

PI3K/AKT-IN-1

Also known as 4-(4-methoxyphenyl)-2-methylsulfanyl-6-[(2E)-2-[(3,4,5-trimethoxyphenyl)methylidene]hydrazinyl]pyrimidine-5-carbonitrile

PI3K/AKT-IN-1 is an effective dual inhibitor of PI3K/AKT (with IC50 values of 6·99 μM, 4·01 μM, and 3·36 μM for PI3Kα, PI3Kδ, and AKT, respectively)· It has anti-cancer activity by inhibiting the PI3K/AKT pathway and inducing caspase 3-dependent apoptosis

ChemicalCAS3033069-84-7MW465.52FormulaC23H23N5O4S
CAS number
3033069-84-7
Molecular weight
465.52
Formula
C23H23N5O4S
Solubility
DMSO ： 50 mg/mL (107·41 mM; Need ultrasonic)
InChIKey
WGUUTVSZGSTNKU-DHRITJCHSA-N
Catalogue number
GC69706
Brand
GLPBIO
Computed properties PubChem CID 168008619 · XLogP 4.8 · TPSA 136 Ų · H-bond donors 1
XLogP
4.8
TPSA
136 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
9
Heavy atoms
33

SMILES COC1=CC=C(C=C1)C2=C(C(=NC(=N2)SC)N/N=C/C3=CC(=C(C(=C3)OC)OC)OC)C#N

Computed descriptors from PubChem (CID 168008619), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.