Loading...
Chemical structure of PI3Kδ-IN-1

GC65199

PI3Kδ-IN-1

Also known as 2-(4-acetyl-3,3-dimethyl-2-oxopiperazin-1-yl)-4-[4-amino-5-(trifluoromethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]benzonitrile

PI3Kδ-IN-1 is a potent, selective, and efficacious PI3Kδ inhibitor with an IC50 of 1·7 nM

ChemicalCAS1911564-39-0MW471.44FormulaC22H20F3N7O2
CAS number
1911564-39-0
Molecular weight
471.44
Formula
C22H20F3N7O2
Solubility
DMSO ： 62·5 mg/mL (132·57 mM; Need ultrasonic)
InChIKey
ZDXIDBRGTYDHBQ-UHFFFAOYSA-N
Catalogue number
GC65199
Brand
GLPBIO
Computed properties PubChem CID 132220479 · XLogP 1.6 · TPSA 121 Ų · H-bond donors 1
XLogP
1.6
TPSA
121 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
2
Heavy atoms
34

SMILES CC(=O)N1CCN(C(=O)C1(C)C)C2=C(C=CC(=C2)C3=CC(=C4N3N=CN=C4N)C(F)(F)F)C#N

Computed descriptors from PubChem (CID 132220479), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.