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Chemical structure of OTS193320

GC69636

OTS193320

Also known as 4-N-[2-(5-chloro-2,4-dimethoxyphenyl)imidazo[1,2-a]pyridin-7-yl]-1-N-[(4-nitrophenyl)methyl]cyclohexane-1,4-diamine

OTS193320 is an imidazopyridine compound, a SUV39H2 methyltransferase activity inhibitor· OTS193320 reduces the global histone H3 lysine 9 trimethylation level in breast cancer cells and induces apoptosis cell death· Compared to single-agent OTS193320 or DOX, the combination of OTS193320 with Doxorubicin (DOX; A) can lead to a decrease in γ-H2AX levels and cancer cell viability

ChemicalCAS2093401-33-1MW536.02FormulaC28H30ClN5O4
CAS number
2093401-33-1
Molecular weight
536.02
Formula
C28H30ClN5O4
Solubility
DMSO ： 62·5 mg/mL (116·60 mM; ultrasonic and warming and heat to 60°C)
InChIKey
LGYQCBXDHOTMJD-UHFFFAOYSA-N
Catalogue number
GC69636
Brand
GLPBIO
Computed properties PubChem CID 134817271 · XLogP 6.2 · TPSA 106 Ų · H-bond donors 2
XLogP
6.2
TPSA
106 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
38

SMILES COC1=CC(=C(C=C1C2=CN3C=CC(=CC3=N2)NC4CCC(CC4)NCC5=CC=C(C=C5)[N+](=O)[O-])Cl)OC

Computed descriptors from PubChem (CID 134817271), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.