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Chemical structure of OTS964

GC16511

OTS964

OTS964 is an orally active, high affinity and selective TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor with an IC50 of 28 nM· OTS964 is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM

ChemicalCAS1338545-07-5MW378.49FormulaC22H22N2O2S
CAS number
1338545-07-5
Molecular weight
378.49
Formula
C22H22N2O2S
Solubility
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS(pH 7·2) (1:2): 0·25 mg/ml
Catalogue number
GC16511
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.