GC69572
NLRP3-IN-13
Also known as 2-(2-oxo-1,3-benzoxazol-3-yl)-N-[(5-thiophen-3-yl-3-pyridinyl)methyl]acetamide
NLRP3-IN-13 (compound C77 in reference patent) is an effective selective NLRP3 inhibitor (IC50: 2·1 μM)· It inhibits NLRP3 and NLRC4 inflammasomes, and suppresses IL-1β production mediated by NLRP3· NLRP3-IN-13 also inhibits NLRP3 ATPase activity· It can be used for research on neuroinflammatory diseases
ChemicalCAS1704638-35-6MW365.41FormulaC19H15N3O3S
- CAS number
- 1704638-35-6
- Molecular weight
- 365.41
- Formula
- C19H15N3O3S
- Solubility
- DMSO ： 50 mg/mL (136·83 mM; Need ultrasonic)
- InChIKey
- HUHGLJIKNHWNBN-UHFFFAOYSA-N
- Catalogue number
- GC69572
- Brand
- GLPBIO
Computed properties PubChem CID 86265099 · XLogP 2.4 · TPSA 99.8 Ų · H-bond donors 1
- XLogP
- 2.4
- TPSA
- 99.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 26
SMILES C1=CC=C2C(=C1)N(C(=O)O2)CC(=O)NCC3=CC(=CN=C3)C4=CSC=C4
Computed descriptors from PubChem (CID 86265099), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il