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Chemical structure of NLRP3-IN-10

GC69570

NLRP3-IN-10

Also known as (E)-3-(4-bromo-2,5-dimethoxyphenyl)-1-(4-fluorophenyl)prop-2-en-1-one

NLRP3-IN-10 is a potent inhibitor of NLRP3 that inhibits IL-1β with an IC50 of 251·1 nM· NLRP3-IN-10 can reduce ASC speck formation and inhibit NLRP3 inflammasome activation

ChemicalCAS2641826-39-1MW365.19FormulaC17H14BrFO3
CAS number
2641826-39-1
Molecular weight
365.19
Formula
C17H14BrFO3
Solubility
DMSO ： 100 mg/mL (273·83 mM; Need ultrasonic)
InChIKey
ZXMIFRJYIRYWTC-VMPITWQZSA-N
Catalogue number
GC69570
Brand
GLPBIO
Computed properties PubChem CID 156702996 · XLogP 4.4 · TPSA 35.5 Ų · H-bond donors 0
XLogP
4.4
TPSA
35.5 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
22

SMILES COC1=CC(=C(C=C1/C=C/C(=O)C2=CC=C(C=C2)F)OC)Br

Computed descriptors from PubChem (CID 156702996), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.