Loading...
Chemical structure of IACS-15414

GC69250

IACS-15414

Also known as 6-[(3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methylpyrimidin-4-one

IACS-15414 is an orally effective SHP2 inhibitor with an IC50 value of 122 nM

ChemicalCAS2411321-29-2MW423.34FormulaC20H24Cl2N4O2
CAS number
2411321-29-2
Molecular weight
423.34
Formula
C20H24Cl2N4O2
InChIKey
WYUIJDCKOPRFJO-HXPMCKFVSA-N
Catalogue number
GC69250
Brand
GLPBIO
Computed properties PubChem CID 146364381 · XLogP 2.4 · TPSA 71.2 Ų · H-bond donors 1
XLogP
2.4
TPSA
71.2 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
28

SMILES C[C@H]1[C@H](C2(CCN(CC2)C3=CC(=O)N(C(=N3)C)C4=C(C(=CC=C4)Cl)Cl)CO1)N

Computed descriptors from PubChem (CID 146364381), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.