GC62345
IACS-13909
IACS-13909 is a selective, potent and orally active SHP2 allosteric inhibitor with an IC50 of 15·7 nM and a Kd of 32 nM· IACS-13909 is more selective for SHP2 than other phosphatases (including SHP1)· IACS-13909 has antitumor activities and suppresses MAPK pathway signaling in receptor tyrosine kinases (RTK)-dependent cancers
ChemicalCAS2160546-07-4MW377.27FormulaC17H18Cl2N6
- CAS number
- 2160546-07-4
- Molecular weight
- 377.27
- Formula
- C17H18Cl2N6
- Solubility
- DMSO ： 10 mg/mL (26·51 mM; Need ultrasonic)
- Catalogue number
- GC62345
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il