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Chemical structure of IACS-10759

GC19194

IACS-10759

Also known as 5-[5-methyl-1-[[3-(4-methylsulfonylpiperidin-1-yl)phenyl]methyl]-1,2,4-triazol-3-yl]-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole

IACS-10759 (IACS-010759) is an oxidative phosphorylation inhibitor, IACS-10759 is a potent inhibitor of complex I of oxidative phosphorylation ( OXPHOS )

ChemicalCAS1570496-34-2MW562.56FormulaC25H25F3N6O4S
CAS number
1570496-34-2
Molecular weight
562.56
Formula
C25H25F3N6O4S
Solubility
DMSO : 62·5 mg/mL (111·10 mM);Water : < 0·1 mg/mL (insoluble)
InChIKey
HWJWNWZJUYCGKV-UHFFFAOYSA-N
Catalogue number
GC19194
Brand
GLPBIO
Computed properties PubChem CID 86711931 · XLogP 4.8 · TPSA 125 Ų · H-bond donors 0
XLogP
4.8
TPSA
125 Ų
H-bond donors
0
H-bond acceptors
12
Rotatable bonds
7
Heavy atoms
39

SMILES CC1=NC(=NN1CC2=CC(=CC=C2)N3CCC(CC3)S(=O)(=O)C)C4=NC(=NO4)C5=CC=C(C=C5)OC(F)(F)F

Computed descriptors from PubChem (CID 86711931), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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