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Chemical structure of AK-778-XXMU

GC68632

AK-778-XXMU

Also known as 1-[(3-chlorophenyl)methyl]-3-hydroxy-3-(2-oxo-2-pyridin-2-ylethyl)indol-2-one

AK-778-XXMU is an effective inhibitor of DNA binding 2 (ID2) antagonist, with a KD of 129 nM· AK-778-XXMU can inhibit the migration and invasion of glioma cell lines, induce apoptosis, and more importantly, slow down tumor growth

ChemicalCAS1227045-76-2MW392.83FormulaC22H17ClN2O3
CAS number
1227045-76-2
Molecular weight
392.83
Formula
C22H17ClN2O3
InChIKey
JJOIKBZRLCEZOR-UHFFFAOYSA-N
Catalogue number
GC68632
Brand
GLPBIO
Computed properties PubChem CID 45259071 · XLogP 3.5 · TPSA 70.5 Ų · H-bond donors 1
XLogP
3.5
TPSA
70.5 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
28

SMILES C1=CC=C2C(=C1)C(C(=O)N2CC3=CC(=CC=C3)Cl)(CC(=O)C4=CC=CC=N4)O

Computed descriptors from PubChem (CID 45259071), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.