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Chemical structure of GSK-3β inhibitor 11

GC66032

GSK-3β inhibitor 11

Also known as 2-(1,3-dioxoisoindol-2-yl)-N-[4-(3-methoxyphenyl)-1,3-thiazol-2-yl]acetamide

GSK-3β inhibitor 11 (compound 21) is a glycogen synthase kinase-3β (GSK-3β) inhibitor (IC50=10·02 μM)· GSK-3β inhibitor 11 can be used in neurodegenerative disease research

ChemicalCAS536731-65-4MW393.42FormulaC20H15N3O4S
CAS number
536731-65-4
Molecular weight
393.42
Formula
C20H15N3O4S
Solubility
DMSO : 20·83 mg/mL (52·95 mM; ultrasonic and warming and heat to 60°C)
InChIKey
OLPPQDIVHUSKKX-UHFFFAOYSA-N
Catalogue number
GC66032
Brand
GLPBIO
Computed properties PubChem CID 1579446 · XLogP 2.8 · TPSA 117 Ų · H-bond donors 1
XLogP
2.8
TPSA
117 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
28

SMILES COC1=CC=CC(=C1)C2=CSC(=N2)NC(=O)CN3C(=O)C4=CC=CC=C4C3=O

Computed descriptors from PubChem (CID 1579446), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.