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Chemical structure of MPT0E028

GC65965

MPT0E028

Also known as (E)-3-[1-(benzenesulfonyl)-2,3-dihydroindol-5-yl]-N-hydroxyprop-2-enamide

MPT0E028 is an orally active and selective HDAC inhibitor with IC50s of 53·0 nM, 106·2 nM, 29·5 nM for HDAC1, HDAC2 and HDAC6, respectively· MPT0E028 reduces the viability of B-cell lymphomas by inducing apoptosis and possesses potent direct Akt targeting ability and reduces Akt phosphorylation in B-cell lymphoma· MPT0E028 has good anticancer activity

ChemicalCAS1338320-94-7MW344.38FormulaC17H16N2O4S
CAS number
1338320-94-7
Molecular weight
344.38
Formula
C17H16N2O4S
InChIKey
MGTIFSBCGGAZDB-VQHVLOKHSA-N
Catalogue number
GC65965
Brand
GLPBIO
Computed properties PubChem CID 53464642 · XLogP 1.9 · TPSA 95.1 Ų · H-bond donors 2
XLogP
1.9
TPSA
95.1 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
24

SMILES C1CN(C2=C1C=C(C=C2)/C=C/C(=O)NO)S(=O)(=O)C3=CC=CC=C3

Computed descriptors from PubChem (CID 53464642), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.