Loading...
Chemical structure of MPT0B098

GB40282

MPT0B098

Also known as 1-(4-methoxyphenyl)sulfonyl-7-pyridin-4-yl-2,3-dihydroindole

Microtubule inhibitor that binds to the colchicine-binding site of tubulin and suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability· MPT0B098 arrests cells in the G2-M phase and subsequently induces cell apoptosis· In addition, MPT0B098 effectively suppresses VEGF-induced cell migration and capillary-like tube formation of HUVECs· MPT0B098 not only inhibited the expression levels of HIF-1α protein but also destabilized HIF-1α mRNA

ChemicalCAS1254363-89-7MW366.43FormulaC20H18N2O3S
CAS number
1254363-89-7
Molecular weight
366.43
Formula
C20H18N2O3S
InChIKey
AGYCYVPAEQVWJT-UHFFFAOYSA-N
Catalogue number
GB40282
Brand
GLPBIO
Computed properties PubChem CID 50898338 · XLogP 3.2 · TPSA 67.9 Ų · H-bond donors 0
XLogP
3.2
TPSA
67.9 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
26

SMILES COC1=CC=C(C=C1)S(=O)(=O)N2CCC3=C2C(=CC=C3)C4=CC=NC=C4

Computed descriptors from PubChem (CID 50898338), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.