GC65886
BI-853520
Also known as 2-fluoro-5-methoxy-4-[[4-[(2-methyl-3-oxo-1H-isoindol-4-yl)oxy]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-N-(1-methylpiperidin-4-yl)benzamide
BI 853520 (IN-10018) is an orally active and potent focal adhesion kinase (FAK) inhibitor (recombinant FAK IC50=1nM)· BI 853520 shows anti-proliferative activity against cancer cells
ChemicalCAS1227948-82-4MW588.55FormulaC28H28F4N6O4
- CAS number
- 1227948-82-4
- Molecular weight
- 588.55
- Formula
- C28H28F4N6O4
- InChIKey
- ULMMVBPTWVRPSI-UHFFFAOYSA-N
- Catalogue number
- GC65886
- Brand
- GLPBIO
Computed properties PubChem CID 46207957 · XLogP 3.8 · TPSA 109 Ų · H-bond donors 2
- XLogP
- 3.8
- TPSA
- 109 Ų
- H-bond donors
- 2
- H-bond acceptors
- 12
- Rotatable bonds
- 7
- Heavy atoms
- 42
SMILES CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2F)NC3=NC=C(C(=N3)OC4=CC=CC5=C4C(=O)N(C5)C)C(F)(F)F)OC
Computed descriptors from PubChem (CID 46207957), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il