Loading...
Chemical structure of BI-9321 trihydrochloride

GC39663

BI-9321 trihydrochloride

Also known as [4-[5-(7-fluoroquinolin-4-yl)-1-methylimidazol-4-yl]-3,5-dimethylphenyl]methanamine;trihydrochloride

BI-9321 trihydrochloride is a potent, selective and cellular active nuclear receptor-binding SET domain 3 (NSD3)-PWWP1 domain antagonist with a Kd value of 166 nM· BI-9321 trihydrochloride is inactive against NSD2-PWWP1 and NSD3-PWWP2· BI-9321 trihydrochloride specifically disrupts histone interactions of the NSD3-PWWP1 domain with an IC50 of 1·2 μM in U2OS cells

ChemicalCAS2387510-87-2MW469.81FormulaC22H24Cl3FN4
CAS number
2387510-87-2
Molecular weight
469.81
Formula
C22H24Cl3FN4
Solubility
DMSO： 250 mg/mL (532·13 mM)
InChIKey
DCDXMBVQCRHZMW-UHFFFAOYSA-N
Catalogue number
GC39663
Brand
GLPBIO
Computed properties PubChem CID 145874876 · TPSA 56.7 Ų · H-bond donors 4 · H-bond acceptors 4
TPSA
56.7 Ų
H-bond donors
4
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
30

SMILES CC1=CC(=CC(=C1C2=C(N(C=N2)C)C3=C4C=CC(=CC4=NC=C3)F)C)CN.Cl.Cl.Cl

Computed descriptors from PubChem (CID 145874876), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.