Loading...
Chemical structure of Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE

GC65552

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE

Also known as [4-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]propanoyl]amino]propanoyl]amino]-4-oxobutanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylcarbamate

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) is a potent anticancer agent, which can be specific activated by tumor microenvironment· Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE can suppress tumor growth in mice (extracted from patent CN104147612A)

ChemicalCAS1638970-46-3MW1316.58FormulaC67H101N11O16
CAS number
1638970-46-3
Molecular weight
1316.58
Formula
C67H101N11O16
Solubility
DMSO ： 180 mg/mL (136·72 mM; Need ultrasonic)
InChIKey
AWJDDTWUHNATEN-NAMAUAOVSA-N
Catalogue number
GC65552
Brand
GLPBIO
Computed properties PubChem CID 164886611 · XLogP 3.1 · TPSA 364 Ų · H-bond donors 8
XLogP
3.1
TPSA
364 Ų
H-bond donors
8
H-bond acceptors
16
Rotatable bonds
38
Heavy atoms
94

SMILES CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCCCCN4C(=O)C=CC4=O

Computed descriptors from PubChem (CID 164886611), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.