Loading...
Chemical structure of Mal-VC-PAB-DM1

GC63388

Mal-VC-PAB-DM1

Also known as [(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[[4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methoxycarbonyl-methylamino]propanoate

Mal-VC-PAB-DM1 is a drug-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker Mal-VC-PAB

ChemicalCAS1464051-44-2MW1248.81FormulaC61H82ClN9O17
CAS number
1464051-44-2
Molecular weight
1248.81
Formula
C61H82ClN9O17
Solubility
DMSO ： 75 mg/mL (60·06 mM; Need ultrasonic)
InChIKey
HRJSYKXPHXEHQA-GZOBIGBUSA-N
Catalogue number
GC63388
Brand
GLPBIO
Computed properties PubChem CID 90455140 · XLogP 2.9 · TPSA 346 Ų · H-bond donors 7
XLogP
2.9
TPSA
346 Ų
H-bond donors
7
H-bond acceptors
17
Rotatable bonds
25
Heavy atoms
88

SMILES C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)OCC5=CC=C(C=C5)NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](C(C)C)NC(=O)CCCCCN6C(=O)C=CC6=O)C)\C)OC)(NC(=O)O2)O

Computed descriptors from PubChem (CID 90455140), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.