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Chemical structure of Mal-VC-PAB-PNP

GC73174

Mal-VC-PAB-PNP

Also known as [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate

Mal-VC-PAB-PNP is a cleavable ADC linker

ChemicalCAS1096584-62-1MW695.68FormulaC32H37N7O11
CAS number
1096584-62-1
Molecular weight
695.68
Formula
C32H37N7O11
Solubility
DMSO : 125 mg/mL (179·68 mM; Need ultrasonic)
InChIKey
WZLBRPXGGXMQRU-CUBQBAPOSA-N
Catalogue number
GC73174
Brand
GLPBIO
Computed properties PubChem CID 142463728 · XLogP 1.3 · TPSA 261 Ų · H-bond donors 5
XLogP
1.3
TPSA
261 Ų
H-bond donors
5
H-bond acceptors
11
Rotatable bonds
18
Heavy atoms
50

SMILES CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)COC(=O)OC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CCN3C(=O)C=CC3=O

Computed descriptors from PubChem (CID 142463728), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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