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Chemical structure of Indisulam

GC65549

Indisulam

Also known as 4-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide

Indisulam (E 7070) is a carbonic anhydrase inhibitor with anticancer activity· Indisulam (E 7070) is a sulfonamide agent that targets the G1 phase of the cell cycle· Indisulam (E 7070) causes a blockade in the G1/S transition through inhibition of the activation of both CDK2 and cyclin E· Indisulam (E 7070) targets splicing by inducing RBM39 degradation via recruitment to DCAF15

ChemicalCAS165668-41-7MW385.85FormulaC14H12ClN3O4S2
CAS number
165668-41-7
Molecular weight
385.85
Formula
C14H12ClN3O4S2
Solubility
DMSO : 100 mg/mL (259·17 mM; Need ultrasonic)
InChIKey
SETFNECMODOHTO-UHFFFAOYSA-N
Catalogue number
GC65549
Brand
GLPBIO
Computed properties PubChem CID 216468 · XLogP 1.8 · TPSA 139 Ų · H-bond donors 3
XLogP
1.8
TPSA
139 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
24

SMILES C1=CC2=C(C(=C1)NS(=O)(=O)C3=CC=C(C=C3)S(=O)(=O)N)NC=C2Cl

Computed descriptors from PubChem (CID 216468), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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