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Chemical structure of Indirubin-3'-oxime

GC12661

Indirubin-3'-oxime

Also known as 3-(3-nitroso-1H-indol-2-yl)-1H-indol-2-ol

Indirubin-3'-oxime is a potent GSK-3β inhibitor, and weakly inhibits 5-Lipoxygenase, with IC50s of 22 nM and 7·8-10 μM, respectively; Indirubin-3'-oxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM

ChemicalCAS160807-49-8MW277.28FormulaC16H11N3O2
CAS number
160807-49-8
Molecular weight
277.28
Formula
C16H11N3O2
Solubility
DMF： 10 mg/ml,DMSO： 10 mg/ml,DMSO：PBS (pH 7·2)(1：5)： 0·15 mg/ml,Ethanol： 2 mg/ml
InChIKey
FQCPPVRJPILDIK-UHFFFAOYSA-N
Catalogue number
GC12661
Brand
GLPBIO
Computed properties PubChem CID 3707 · XLogP 3.2 · TPSA 81.2 Ų · H-bond donors 3
XLogP
3.2
TPSA
81.2 Ų
H-bond donors
3
H-bond acceptors
3
Rotatable bonds
1
Heavy atoms
21

SMILES C1=CC=C2C(=C1)C(=C(N2)O)C3=C(C4=CC=CC=C4N3)N=O

Computed descriptors from PubChem (CID 3707), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.