GC12975
Indirubin
Also known as 2-(2-hydroxy-1H-indol-3-yl)indol-3-one
Indirubin is a potent inhibitor of cyclin-dependent kinases (CDKs) (IC50: 50-100nmol/L) and glycogen synthase kinase-3beta (GSK-3β) (IC50: 5-50nmol/L), with oral administration characteristics
ChemicalCAS479-41-4MW262.26FormulaC16H10N2O2
- CAS number
- 479-41-4
- Molecular weight
- 262.26
- Formula
- C16H10N2O2
- Solubility
- DMF>1 mg/ml, DMSO>10 mg/ml
- InChIKey
- JNLNPCNGMHKCKO-UHFFFAOYSA-N
- Catalogue number
- GC12975
- Brand
- GLPBIO
Computed properties PubChem CID 10177 · XLogP 2.7 · TPSA 65.5 Ų · H-bond donors 2
- XLogP
- 2.7
- TPSA
- 65.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Rotatable bonds
- 1
- Heavy atoms
- 20
SMILES C1=CC=C2C(=C1)C(=C(N2)O)C3=NC4=CC=CC=C4C3=O
Computed descriptors from PubChem (CID 10177), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il