Loading...
Chemical structure of AZD8154

GC65507

AZD8154

Also known as 2-[(1S)-1-cyclopropylethyl]-5-[4-methyl-2-[[6-(2-oxopyrrolidin-1-yl)-2-pyridinyl]amino]-1,3-thiazol-5-yl]-7-methylsulfonyl-3H-isoindol-1-one

AZD8154 is a novel inhaled selective PI3Kγδ dual inhibitor targeting airway inflammatory disease

ChemicalCAS2215022-45-8MW551.68FormulaC27H29N5O4S2
CAS number
2215022-45-8
Molecular weight
551.68
Formula
C27H29N5O4S2
Solubility
DMSO ： 25 mg/mL (45·32 mM; Need ultrasonic)
InChIKey
XOMFDZJQLSPGGV-INIZCTEOSA-N
Catalogue number
GC65507
Brand
GLPBIO
Computed properties PubChem CID 141754136 · XLogP 3.4 · TPSA 149 Ų · H-bond donors 1
XLogP
3.4
TPSA
149 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
38

SMILES CC1=C(SC(=N1)NC2=NC(=CC=C2)N3CCCC3=O)C4=CC5=C(C(=C4)S(=O)(=O)C)C(=O)N(C5)[C@@H](C)C6CC6

Computed descriptors from PubChem (CID 141754136), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.