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Chemical structure of AZD8329

GC35449

AZD8329

Also known as 4-[4-(2-adamantylcarbamoyl)-5-tert-butylpyrazol-1-yl]benzoic acid

AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3

ChemicalCAS1048668-70-7MW421.53FormulaC25H31N3O3
CAS number
1048668-70-7
Molecular weight
421.53
Formula
C25H31N3O3
Solubility
DMSO： 62·5 mg/mL (148·27 mM)
InChIKey
XWBXJBSVYVJAMZ-UHFFFAOYSA-N
Catalogue number
GC35449
Brand
GLPBIO
Computed properties PubChem CID 25006684 · XLogP 4.8 · TPSA 84.2 Ų · H-bond donors 2
XLogP
4.8
TPSA
84.2 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
31

SMILES CC(C)(C)C1=C(C=NN1C2=CC=C(C=C2)C(=O)O)C(=O)NC3C4CC5CC(C4)CC3C5

Computed descriptors from PubChem (CID 25006684), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.