
GC12576
AZD8186
Also known as 8-[(1R)-1-(3,5-difluoroanilino)ethyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide
Potent and selective inhibitor of PI3Kβ and PI3Kδ
ChemicalCAS1627494-13-6MW457.47FormulaC24H25F2N3O4
- CAS number
- 1627494-13-6
- Molecular weight
- 457.47
- Formula
- C24H25F2N3O4
- Solubility
- ≥ 45·7mg/mL in DMSO with ultrasonic
- InChIKey
- LMJFJIDLEAWOQJ-CQSZACIVSA-N
- Catalogue number
- GC12576
- Brand
- GLPBIO
Computed properties PubChem CID 52913813 · XLogP 3 · TPSA 71.1 Ų · H-bond donors 1
- XLogP
- 3
- TPSA
- 71.1 Ų
- H-bond donors
- 1
- H-bond acceptors
- 8
- Rotatable bonds
- 5
- Heavy atoms
- 33
SMILES C[C@H](C1=CC(=CC2=C1OC(=CC2=O)N3CCOCC3)C(=O)N(C)C)NC4=CC(=CC(=C4)F)F
Computed descriptors from PubChem (CID 52913813), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il