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Chemical structure of AZD8186

GC12576

AZD8186

Also known as 8-[(1R)-1-(3,5-difluoroanilino)ethyl]-N,N-dimethyl-2-morpholin-4-yl-4-oxochromene-6-carboxamide

Potent and selective inhibitor of PI3Kβ and PI3Kδ

ChemicalCAS1627494-13-6MW457.47FormulaC24H25F2N3O4
CAS number
1627494-13-6
Molecular weight
457.47
Formula
C24H25F2N3O4
Solubility
≥ 45·7mg/mL in DMSO with ultrasonic
InChIKey
LMJFJIDLEAWOQJ-CQSZACIVSA-N
Catalogue number
GC12576
Brand
GLPBIO
Computed properties PubChem CID 52913813 · XLogP 3 · TPSA 71.1 Ų · H-bond donors 1
XLogP
3
TPSA
71.1 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
33

SMILES C[C@H](C1=CC(=CC2=C1OC(=CC2=O)N3CCOCC3)C(=O)N(C)C)NC4=CC(=CC(=C4)F)F

Computed descriptors from PubChem (CID 52913813), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.