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Chemical structure of BI 653048

GC65345

BI 653048

Also known as 2-[(4R)-4-[(5-ethylsulfonyl-1H-pyrrolo[2,3-c]pyridin-2-yl)methyl]-5,5,5-trifluoro-4-hydroxy-2-methylpentan-2-yl]-5-fluorobenzamide

BI 653048 is a selective and orally active nonsteroidal?glucocorticoid (GC)?agonist with an IC50 value of 55 nM

ChemicalCAS1198784-72-3MW515.52FormulaC23H25F4N3O4S
CAS number
1198784-72-3
Molecular weight
515.52
Formula
C23H25F4N3O4S
Solubility
DMSO ： 100 mg/mL (193·98 mM; Need ultrasonic)
InChIKey
AUIFRJWXYUNPPV-QFIPXVFZSA-N
Catalogue number
GC65345
Brand
GLPBIO
Computed properties PubChem CID 44543970 · XLogP 3.7 · TPSA 135 Ų · H-bond donors 3
XLogP
3.7
TPSA
135 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
35

SMILES CCS(=O)(=O)C1=NC=C2C(=C1)C=C(N2)C[C@](CC(C)(C)C3=C(C=C(C=C3)F)C(=O)N)(C(F)(F)F)O

Computed descriptors from PubChem (CID 44543970), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.