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Chemical structure of BI 224436

GC35510

BI 224436

Also known as (2S)-2-[2-methyl-4-(2-oxa-8-azatricyclo[7.3.1.05,13]trideca-1(13),5,7,9,11-pentaen-10-yl)quinolin-3-yl]-2-[(2-methylpropan-2-yl)oxy]acetic acid

BI 224436 is a novel HIV-1 noncatalytic site integrase inhibitor with EC50 values of less than 15 nM against different HIV-1 laboratory strains

ChemicalCAS1155419-89-8MW442.51FormulaC27H26N2O4
CAS number
1155419-89-8
Molecular weight
442.51
Formula
C27H26N2O4
Solubility
DMSO： ≥ 50 mg/mL (112·99 mM)
InChIKey
MIXIIJCBELCMCZ-VWLOTQADSA-N
Catalogue number
GC35510
Brand
GLPBIO
Computed properties PubChem CID 66561902 · XLogP 4.9 · TPSA 81.5 Ų · H-bond donors 1
XLogP
4.9
TPSA
81.5 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
33

SMILES CC1=NC2=CC=CC=C2C(=C1[C@@H](C(=O)O)OC(C)(C)C)C3=C4C5=C(C=C3)OCCC5=CC=N4

Computed descriptors from PubChem (CID 66561902), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.