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Chemical structure of BI 689648

GC32419

BI 689648

Also known as 6-[5-(methoxymethyl)-3-pyridinyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide

BI 689648 is a novel, highly selective aldosterone synthase inhibitor which can inhibit CYP11B1 and CYP11B2 with IC50s of 310 and 2·1 nM, respectively

ChemicalCAS1633009-87-6MW298.34FormulaC16H18N4O2
CAS number
1633009-87-6
Molecular weight
298.34
Formula
C16H18N4O2
Solubility
DMSO ： 30 mg/mL (100·56 mM)
InChIKey
DJFDCVNQDFICKV-UHFFFAOYSA-N
Catalogue number
GC32419
Brand
GLPBIO
Computed properties PubChem CID 86305663 · XLogP 0.6 · TPSA 81.3 Ų · H-bond donors 1
XLogP
0.6
TPSA
81.3 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
22

SMILES COCC1=CC(=CN=C1)C2=CC3=C(N=C2)N(CCC3)C(=O)N

Computed descriptors from PubChem (CID 86305663), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.