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Chemical structure of IRES-C11

GC65188

IRES-C11

Also known as 3,4-dichloro-1-[(2,4-dimethoxyphenyl)methyl]pyrrole-2,5-dione

IRES-C11 is a spectfic c-MYC internal ribosome entry site (IRES) translation inhibitor· IRES-C11 blocks the interaction of a requisite c-MYC IRES trans-acting factor, heterogeneous nuclear ribonucleoprotein A1, with its IRES· IRES-C11 does not inhibits BAG-1, XIAP and p53 IRESes

ChemicalCAS342416-30-2MW316.14FormulaC13H11Cl2NO4
CAS number
342416-30-2
Molecular weight
316.14
Formula
C13H11Cl2NO4
Solubility
DMSO ： 250 mg/mL (790·79 mM; Need ultrasonic)
InChIKey
SYBFPEVCOHEALP-UHFFFAOYSA-N
Catalogue number
GC65188
Brand
GLPBIO
Computed properties PubChem CID 353999 · XLogP 2.6 · TPSA 55.8 Ų · H-bond donors 0
XLogP
2.6
TPSA
55.8 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
20

SMILES COC1=CC(=C(C=C1)CN2C(=O)C(=C(C2=O)Cl)Cl)OC

Computed descriptors from PubChem (CID 353999), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.