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Chemical structure of FCPR03

GC65173

FCPR03

Also known as 3-(cyclopropylmethoxy)-4-(difluoromethoxy)-N-propan-2-ylbenzamide

FCPR03 is a potent and selective phosphodiesterase 4 (PDE4) inhibitor with IC50 values of 60 nM, 31 nM and 47 nM for PDE4 catalytic domain, PDE4B1 and PDE4D7, respectively

ChemicalCAS1917347-65-9MW299.31FormulaC15H19F2NO3
CAS number
1917347-65-9
Molecular weight
299.31
Formula
C15H19F2NO3
Solubility
DMSO : 100 mg/mL (334·10 mM; Need ultrasonic)
InChIKey
DLTIJXDCEGNJEW-UHFFFAOYSA-N
Catalogue number
GC65173
Brand
GLPBIO
Computed properties PubChem CID 146681183 · XLogP 3.6 · TPSA 47.6 Ų · H-bond donors 1
XLogP
3.6
TPSA
47.6 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
21

SMILES CC(C)NC(=O)C1=CC(=C(C=C1)OC(F)F)OCC2CC2

Computed descriptors from PubChem (CID 146681183), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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