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Chemical structure of BI8626

GC65148

BI8626

Also known as N-[[3-(aminomethyl)phenyl]methyl]-4-(4-benzylpiperazin-1-yl)pyrimido[5,4-d]pyrimidin-8-amine

BI8626 is a specific inhibitor of the ubiquitin ligase HUWE1 with an IC50 of 0·9 μM

ChemicalCAS1875036-75-1MW440.54FormulaC25H28N8
CAS number
1875036-75-1
Molecular weight
440.54
Formula
C25H28N8
Solubility
DMSO ： 83·33 mg/mL (189·15 mM; Need ultrasonic)
InChIKey
DZDNGSNKWIORRZ-UHFFFAOYSA-N
Catalogue number
GC65148
Brand
GLPBIO
Computed properties PubChem CID 138377589 · XLogP 2.3 · TPSA 96.1 Ų · H-bond donors 2
XLogP
2.3
TPSA
96.1 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
33

SMILES C1CN(CCN1CC2=CC=CC=C2)C3=NC=NC4=C3N=CN=C4NCC5=CC=CC(=C5)CN

Computed descriptors from PubChem (CID 138377589), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.