GC65012
Smurf1-IN-A01
Also known as [4-[4-chloro-3-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]-[4-(5-methylpyrazol-1-yl)phenyl]methanone
Smurf1-IN-A01 (A01) is an ubiquitin ligase Smad ubiquitination regulatory factor-1 (Smurf1) inhibitor with a kd of 3·664 nM, which increases BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation
ChemicalCAS1007647-73-5MW512.93FormulaC22H20ClF3N4O3S
- CAS number
- 1007647-73-5
- Molecular weight
- 512.93
- Formula
- C22H20ClF3N4O3S
- Solubility
- DMSO ： 62·5 mg/mL (121·85 mM; Need ultrasonic)
- InChIKey
- QFYLTUDRXBNZFQ-UHFFFAOYSA-N
- Catalogue number
- GC65012
- Brand
- GLPBIO
Computed properties PubChem CID 17555704 · XLogP 3.9 · TPSA 83.9 Ų · H-bond donors 0
- XLogP
- 3.9
- TPSA
- 83.9 Ų
- H-bond donors
- 0
- H-bond acceptors
- 8
- Rotatable bonds
- 4
- Heavy atoms
- 34
SMILES CC1=CC=NN1C2=CC=C(C=C2)C(=O)N3CCN(CC3)S(=O)(=O)C4=CC(=C(C=C4)Cl)C(F)(F)F
Computed descriptors from PubChem (CID 17555704), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il