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Chemical structure of VU6000918

GC64970

VU6000918

Also known as 5-amino-N-[1-(2,3-difluorophenyl)azetidin-3-yl]-3,4-dimethylthieno[2,3-c]pyridazine-6-carboxamide

VU6000918 is a muscarinic acetylcholine (M4) positive allosteric modulator, with an EC50 of 19 nM for hM4

ChemicalCAS2101737-32-8MW389.42FormulaC18H17F2N5OS
CAS number
2101737-32-8
Molecular weight
389.42
Formula
C18H17F2N5OS
Solubility
DMSO ： 125 mg/mL (320·99 mM; Need ultrasonic)
InChIKey
KWYCAGNWNMBWOL-UHFFFAOYSA-N
Catalogue number
GC64970
Brand
GLPBIO
Computed properties PubChem CID 137635043 · XLogP 3.3 · TPSA 112 Ų · H-bond donors 2
XLogP
3.3
TPSA
112 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
3
Heavy atoms
27

SMILES CC1=C(N=NC2=C1C(=C(S2)C(=O)NC3CN(C3)C4=C(C(=CC=C4)F)F)N)C

Computed descriptors from PubChem (CID 137635043), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
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