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Chemical structure of VU591

GC37930

VU591

Also known as 6-nitro-2-[(6-nitro-1H-benzimidazol-2-yl)methoxymethyl]-1H-benzimidazole

VU591 is a potent, selective renal outer medullary potassium channel (ROMK or Kir1·1) inhibitor, with an IC50 of 0·24 μM

ChemicalCAS1222810-74-3MW368.3FormulaC16H12N6O5
CAS number
1222810-74-3
Molecular weight
368.3
Formula
C16H12N6O5
Solubility
DMSO: 62·5 mg/mL (169·70 mM); Water: < 0·1 mg/mL (insoluble)
InChIKey
ZQPXNYLXYNRFNP-UHFFFAOYSA-N
Catalogue number
GC37930
Brand
GLPBIO
Computed properties PubChem CID 44123657 · XLogP 1.9 · TPSA 158 Ų · H-bond donors 2
XLogP
1.9
TPSA
158 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
27

SMILES C1=CC2=C(C=C1[N+](=O)[O-])NC(=N2)COCC3=NC4=C(N3)C=C(C=C4)[N+](=O)[O-]

Computed descriptors from PubChem (CID 44123657), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.