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Chemical structure of BRD4 Inhibitor-10

GC64960

BRD4 Inhibitor-10

Also known as 2,4-dimethyl-6-[6-(oxan-4-yl)-1-[(1S)-1-phenylethyl]imidazo[4,5-c]pyridin-2-yl]pyridazin-3-one

BRD4 Inhibitor-10 is a potent BRD4-BD1 inhibitor extracted from patent WO2015022332A1, Compound II-25, has an IC50 of 8 nM

ChemicalCAS1660117-38-3MW429.51FormulaC25H27N5O2
CAS number
1660117-38-3
Molecular weight
429.51
Formula
C25H27N5O2
Solubility
DMSO ： 125 mg/mL (291·03 mM; Need ultrasonic)
InChIKey
QNFGQQDKBYVNAS-KRWDZBQOSA-N
Catalogue number
GC64960
Brand
GLPBIO
Computed properties PubChem CID 90647162 · XLogP 3 · TPSA 72.6 Ų · H-bond donors 0
XLogP
3
TPSA
72.6 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
32

SMILES CC1=CC(=NN(C1=O)C)C2=NC3=CN=C(C=C3N2[C@@H](C)C4=CC=CC=C4)C5CCOCC5

Computed descriptors from PubChem (CID 90647162), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.