GC64900
EZM0414 (SETD2-IN-1)
Also known as N-[(1R,3S)-3-(4-acetylpiperazin-1-yl)cyclohexyl]-4-fluoro-7-methyl-1H-indole-2-carboxamide
EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 (IC50=18 nM in SETD2 biochemical assay; IC50=34 nM in cellular assay)· EZM0414 can be used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma
ChemicalCAS2411748-50-8MW400.49FormulaC22H29FN4O2
- CAS number
- 2411748-50-8
- Molecular weight
- 400.49
- Formula
- C22H29FN4O2
- InChIKey
- PGNLXEBQMQHFNK-SJORKVTESA-N
- Catalogue number
- GC64900
- Brand
- GLPBIO
Computed properties PubChem CID 146395245 · XLogP 2.8 · TPSA 68.4 Ų · H-bond donors 2
- XLogP
- 2.8
- TPSA
- 68.4 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 29
SMILES CC1=C2C(=C(C=C1)F)C=C(N2)C(=O)N[C@@H]3CCC[C@@H](C3)N4CCN(CC4)C(=O)C
Computed descriptors from PubChem (CID 146395245), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il