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Chemical structure of EZH2-IN-14

GC73173

EZH2-IN-14

Also known as N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-1-propan-2-yl-6-[6-(4-propan-2-ylpiperazin-1-yl)-3-pyridinyl]indazole-4-carboxamide

EZH2-IN-14 is a selective EZH2 (Histone Metltransferase) inhibitor with an IC50 of 12 nM

ChemicalCAS1979157-17-9MW541.69FormulaC31H39N7O2
CAS number
1979157-17-9
Molecular weight
541.69
Formula
C31H39N7O2
Solubility
DMSO ： 125 mg/mL (230·76 mM; ultrasonic and warming and heat to 60°C)
InChIKey
XHJAGCFBPKQPDU-UHFFFAOYSA-N
Catalogue number
GC73173
Brand
GLPBIO
Computed properties PubChem CID 139211326 · XLogP 3.8 · TPSA 95.4 Ų · H-bond donors 2
XLogP
3.8
TPSA
95.4 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
40

SMILES CC1=CC(=C(C(=O)N1)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C(C)C)C(C)C)C

Computed descriptors from PubChem (CID 139211326), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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