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Chemical structure of BOS-318

GC64637

BOS-318

Also known as 2-[1-[[2-(3,5-dichlorophenyl)-6-[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]oxy-4-pyridinyl]methyl]piperidin-4-yl]acetic acid

BOS-318 is a potent, slowly dissociating, highly selective, and cell-permeable furin inhibitor with IC50 value of 1·9 nM

ChemicalCAS2387633-15-8MW571.5FormulaC28H32Cl2N6O3
CAS number
2387633-15-8
Molecular weight
571.5
Formula
C28H32Cl2N6O3
Solubility
DMSO ： 50 mg/mL (87·49 mM; Need ultrasonic)
InChIKey
AZEJIKZNBHEXCM-UHFFFAOYSA-N
Catalogue number
GC64637
Brand
GLPBIO
Computed properties PubChem CID 146241691 · XLogP 2 · TPSA 94.9 Ų · H-bond donors 1
XLogP
2
TPSA
94.9 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
39

SMILES CN1CCN(CC1)C2=NC=C(C=N2)OC3=CC(=CC(=N3)C4=CC(=CC(=C4)Cl)Cl)CN5CCC(CC5)CC(=O)O

Computed descriptors from PubChem (CID 146241691), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.