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Chemical structure of BOS-172722

GC32846

BOS-172722

Also known as 8-N-(2,2-dimethylpropyl)-2-N-[2-ethoxy-4-(4-methyl-1,2,4-triazol-3-yl)phenyl]-6-methylpyrido[3,4-d]pyrimidine-2,8-diamine

BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 11 nM and 63 nM for MPS1 (1 mM ATP) and P-MPS1, respectively· BOS-172722 also has potential for the study of various forms of breast cancer

ChemicalCAS1578245-44-9MW446.55FormulaC24H30N8O
CAS number
1578245-44-9
Molecular weight
446.55
Formula
C24H30N8O
Solubility
DMSO : < 1 mg/mL (insoluble or slightly soluble);Water : < 0·1 mg/mL (insoluble)
InChIKey
SGWLRDAOCLITOM-UHFFFAOYSA-N
Catalogue number
GC32846
Brand
GLPBIO
Computed properties PubChem CID 73386890 · XLogP 4.3 · TPSA 103 Ų · H-bond donors 2
XLogP
4.3
TPSA
103 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
33

SMILES CCOC1=C(C=CC(=C1)C2=NN=CN2C)NC3=NC=C4C=C(N=C(C4=N3)NCC(C)(C)C)C

Computed descriptors from PubChem (CID 73386890), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
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