GC39483
BO-264
Also known as 3-(4-methoxyphenyl)-N-(2-morpholin-4-ylpyrimidin-4-yl)-1,2-oxazol-5-amine
BO-264 is a highly potent and orally active transforming acidic coiled-coil 3 (TACC3) inhibitor with an IC50 of 188 nM and a Kd of 1·5 nM· BO-264 specifically blocks the function of FGFR3-TACC3 fusion protein· BO-264 induces spindle assembly checkpoint (SAC)-dependent mitotic arrest, DNA damage and apoptosis· BO-264 has broad-spectrum antitumor activity
ChemicalCAS2408648-20-2MW353.38FormulaC18H19N5O3
- CAS number
- 2408648-20-2
- Molecular weight
- 353.38
- Formula
- C18H19N5O3
- Solubility
- DMSO： 50 mg/mL (141·49 mM)
- InChIKey
- WRCGBYNVBFVRTN-UHFFFAOYSA-N
- Catalogue number
- GC39483
- Brand
- GLPBIO
Computed properties PubChem CID 146018837 · XLogP 2.6 · TPSA 85.5 Ų · H-bond donors 1
- XLogP
- 2.6
- TPSA
- 85.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 8
- Rotatable bonds
- 5
- Heavy atoms
- 26
SMILES COC1=CC=C(C=C1)C2=NOC(=C2)NC3=NC(=NC=C3)N4CCOCC4
Computed descriptors from PubChem (CID 146018837), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il