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Chemical structure of AGI-43192

GC64635

AGI-43192

Also known as 8-(4-chlorophenyl)-6-(2-methylindazol-5-yl)-2-(2,2,2-trifluoroethylamino)pyrido[4,3-d]pyrimidin-7-one

AGI-43192 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A)

ChemicalCAS2377491-54-6MW484.86FormulaC23H16ClF3N6O
CAS number
2377491-54-6
Molecular weight
484.86
Formula
C23H16ClF3N6O
Solubility
DMSO : 83·33 mg/mL (171·86 mM; ultrasonic and warming and heat to 60°C)
InChIKey
XXCYDSDPIJJBSI-UHFFFAOYSA-N
Catalogue number
GC64635
Brand
GLPBIO
Computed properties PubChem CID 139551841 · XLogP 3.3 · TPSA 74.9 Ų · H-bond donors 1
XLogP
3.3
TPSA
74.9 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
34

SMILES CN1C=C2C=C(C=CC2=N1)N3C=C4C=NC(=NC4=C(C3=O)C5=CC=C(C=C5)Cl)NCC(F)(F)F

Computed descriptors from PubChem (CID 139551841), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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